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Proteolysis Targeting Chimeras (PROTACs): A Perspective on Integral Membrane Protein Degradation
[Image: see text] Targeted protein degradation (TPD) is a promising therapeutic modality to modulate protein levels and its application promises to reduce the “undruggable” proteome. Among TPD strategies, Proteolysis TArgeting Chimera (PROTAC) technology has shown a tremendous potential with attract...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578132/ https://www.ncbi.nlm.nih.gov/pubmed/36268122 http://dx.doi.org/10.1021/acsptsci.2c00142 |