Effects of Purinergic Receptor Deletion or Pharmacologic Modulation on Pulmonary Inflammation in Mice

[Image: see text] COVID-19 disease is associated with progressive accumulation of SARS-CoV-2-specific mRNA, which is recognized by innate immune receptors, such as TLR3. This in turn leads to dysregulated production of multiple cytokines, including IL-6, IFN-γ, CXCL1, and TNF-α. Excessive production...

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Detalles Bibliográficos
Autores principales: Whitehead, Gregory S., Karcz, Tadeusz P., Tosh, Dilip K., Jung, Young-Hwan, Wen, Zhiwei, Campbell, Ryan G., Gopinatth, Varun, Gao, Zhan-Guo, Jacobson, Kenneth A., Cook, Donald N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578140/
https://www.ncbi.nlm.nih.gov/pubmed/36268115
http://dx.doi.org/10.1021/acsptsci.2c00128

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