Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N(6)-Methyladenosine-Modified RNAs

[Image: see text] YTHDF proteins bind the N(6)-methyladenosine (m6A)-modified mRNAs, influencing their processing, stability, and translation. Therefore, the members of this protein family play crucial roles in gene regulation and several physiological and pathophysiological conditions. YTHDF protei...

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Detalles Bibliográficos
Autores principales: Micaelli, Mariachiara, Dalle Vedove, Andrea, Cerofolini, Linda, Vigna, Jacopo, Sighel, Denise, Zaccara, Sara, Bonomo, Isabelle, Poulentzas, Georgios, Rosatti, Emanuele Filiberto, Cazzanelli, Giulia, Alunno, Laura, Belli, Romina, Peroni, Daniele, Dassi, Erik, Murakami, Shino, Jaffrey, Samie R., Fragai, Marco, Mancini, Ines, Lolli, Graziano, Quattrone, Alessandro, Provenzani, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578143/
https://www.ncbi.nlm.nih.gov/pubmed/36268123
http://dx.doi.org/10.1021/acsptsci.2c00008

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