Successful Treatment of Delayed Localized Necrotizing Inflammatory Myositis After Severe Acute Respiratory Syndrome Coronavirus 2 mRNA-1273 Vaccine: A Case Report

Reported adverse reactions to the mRNA-1273 vaccine (Spikevax, Moderna Inc) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) range from mild, local delayed cutaneous reactions to rarer, more serious reactions such as myocarditis. Here, we describe the presentation and successful...

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Autores principales: Li, Jennifer Chen, Siglin, Jonathan, Marshall, Michael S, Stemmer-Rachamimov, Anat, Bloom, Seth M, Blumenthal, Kimberly G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Novel Id Cases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578160/
https://www.ncbi.nlm.nih.gov/pubmed/36267257
http://dx.doi.org/10.1093/ofid/ofac499
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author Li, Jennifer Chen
Siglin, Jonathan
Marshall, Michael S
Stemmer-Rachamimov, Anat
Bloom, Seth M
Blumenthal, Kimberly G
author_facet Li, Jennifer Chen
Siglin, Jonathan
Marshall, Michael S
Stemmer-Rachamimov, Anat
Bloom, Seth M
Blumenthal, Kimberly G
author_sort Li, Jennifer Chen
collection PubMed
description Reported adverse reactions to the mRNA-1273 vaccine (Spikevax, Moderna Inc) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) range from mild, local delayed cutaneous reactions to rarer, more serious reactions such as myocarditis. Here, we describe the presentation and successful treatment of delayed, localized necrotizing inflammatory myositis following a third dose of the mRNA-1273 SARS-CoV-2 vaccine. To our knowledge, this is the first report of biopsy-confirmed, delayed inflammatory myositis after administration of an mRNA-1273 SARS-CoV-2 vaccine booster.
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spelling pubmed-95781602022-10-19 Successful Treatment of Delayed Localized Necrotizing Inflammatory Myositis After Severe Acute Respiratory Syndrome Coronavirus 2 mRNA-1273 Vaccine: A Case Report Li, Jennifer Chen Siglin, Jonathan Marshall, Michael S Stemmer-Rachamimov, Anat Bloom, Seth M Blumenthal, Kimberly G Open Forum Infect Dis Novel Id Cases Reported adverse reactions to the mRNA-1273 vaccine (Spikevax, Moderna Inc) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) range from mild, local delayed cutaneous reactions to rarer, more serious reactions such as myocarditis. Here, we describe the presentation and successful treatment of delayed, localized necrotizing inflammatory myositis following a third dose of the mRNA-1273 SARS-CoV-2 vaccine. To our knowledge, this is the first report of biopsy-confirmed, delayed inflammatory myositis after administration of an mRNA-1273 SARS-CoV-2 vaccine booster. Oxford University Press 2022-09-27 /pmc/articles/PMC9578160/ /pubmed/36267257 http://dx.doi.org/10.1093/ofid/ofac499 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Novel Id Cases
Li, Jennifer Chen
Siglin, Jonathan
Marshall, Michael S
Stemmer-Rachamimov, Anat
Bloom, Seth M
Blumenthal, Kimberly G
Successful Treatment of Delayed Localized Necrotizing Inflammatory Myositis After Severe Acute Respiratory Syndrome Coronavirus 2 mRNA-1273 Vaccine: A Case Report
title Successful Treatment of Delayed Localized Necrotizing Inflammatory Myositis After Severe Acute Respiratory Syndrome Coronavirus 2 mRNA-1273 Vaccine: A Case Report
title_full Successful Treatment of Delayed Localized Necrotizing Inflammatory Myositis After Severe Acute Respiratory Syndrome Coronavirus 2 mRNA-1273 Vaccine: A Case Report
title_fullStr Successful Treatment of Delayed Localized Necrotizing Inflammatory Myositis After Severe Acute Respiratory Syndrome Coronavirus 2 mRNA-1273 Vaccine: A Case Report
title_full_unstemmed Successful Treatment of Delayed Localized Necrotizing Inflammatory Myositis After Severe Acute Respiratory Syndrome Coronavirus 2 mRNA-1273 Vaccine: A Case Report
title_short Successful Treatment of Delayed Localized Necrotizing Inflammatory Myositis After Severe Acute Respiratory Syndrome Coronavirus 2 mRNA-1273 Vaccine: A Case Report
title_sort successful treatment of delayed localized necrotizing inflammatory myositis after severe acute respiratory syndrome coronavirus 2 mrna-1273 vaccine: a case report
topic Novel Id Cases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578160/
https://www.ncbi.nlm.nih.gov/pubmed/36267257
http://dx.doi.org/10.1093/ofid/ofac499
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