Elevated NRAS expression during DCIS is a potential driver for progression to basal-like properties and local invasiveness

BACKGROUND: Ductal carcinoma in situ (DCIS) is the most common type of in situ premalignant breast cancers. What drives DCIS to invasive breast cancer is unclear. Basal-like invasive breast cancers are aggressive. We have previously shown that NRAS is highly expressed selectively in basal-like subty...

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Detalles Bibliográficos
Autores principales: Zheng, Ze-Yi, Elsarraj, Hanan, Lei, Jonathan T., Hong, Yan, Anurag, Meenakshi, Feng, Long, Kennedy, Hilda, Shen, Yichao, Lo, Flora, Zhao, Zifan, Zhang, Bing, Zhang, Xiang H.-F., Tawfik, Ossama W., Behbod, Fariba, Chang, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578182/
https://www.ncbi.nlm.nih.gov/pubmed/36258226
http://dx.doi.org/10.1186/s13058-022-01565-5

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