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IL-10 producing regulatory B cells are decreased in blood from smokers and COPD patients

BACKGROUND: Two opposing B cell subsets have been defined based on their cytokine profile: IL-6 producing effector B cells (B-effs) versus IL-10 producing regulatory B cells (B-regs) that respectively positively or negatively regulate immune responses. B-regs are decreased and/or impaired in many au...

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Detalles Bibliográficos
Autores principales: Jacobs, Merel, Verschraegen, Sven, Salhi, Bihiyga, Anckaert, Jasper, Mestdagh, Pieter, Brusselle, Guy G., Bracke, Ken R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578234/
https://www.ncbi.nlm.nih.gov/pubmed/36253785
http://dx.doi.org/10.1186/s12931-022-02208-1