Antibacterial Drug Residues in Small Ruminant Edible Tissues and Milk: A Literature Review of Commonly Used Medications in Small Ruminants

SIMPLE SUMMARY: This review is a summary of published studies that contain drug residue depletion data for edible tissues and milk following treatment of sheep and goats. The information is separated by antibiotic class for ease of comparison between studies. This summary is useful for understanding medication residue depletion following extra-label drug use and can be used to help estimate withdrawal intervals in order to help protect the human food chain. ABSTRACT: This review provides a summary of extracted data from the published literature that contains drug residue depletion data for edible tissues and milk following treatment of sheep and goats. Out of 20,234 records obtained during the initial search, data from 177 records were included in this review. The data is separated by antibiotic class for ease of comparison between studies. Extracted data includes the active ingredient, dosing information, animal health status, analytical method and limits of detection, tolerance and maximum residue limit information, and time frames relative to residue absence or detection. This information is useful for understanding drug residue depletion profiles following extra-label use and for estimating withdrawal intervals, in order to protect the human food chain.