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A Systems-Based Analysis of Mono- and Combination Therapy for Carbapenem-Resistant Klebsiella pneumoniae Bloodstream Infections

Antimicrobial resistance is a global threat. As “proof-of-concept,” we employed a system-based approach to identify patient, bacterial, and drug variables contributing to mortality in patients with carbapenem-resistant Klebsiella pneumoniae (CRKp) bloodstream infections exposed to colistin (COL) and...

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Detalles Bibliográficos
Autores principales:	Luterbach, Courtney L., Qiu, Hongqiang, Hanafin, Patrick O., Sharma, Rajnikant, Piscitelli, Joseph, Lin, Feng-Chang, Ilomaki, Jenni, Cober, Eric, Salata, Robert A., Kalayjian, Robert C., Watkins, Richard R., Doi, Yohei, Kaye, Keith S., Nation, Roger L., Bonomo, Robert A., Landersdorfer, Cornelia B., van Duin, David, Rao, Gauri G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578421/ https://www.ncbi.nlm.nih.gov/pubmed/36125299 http://dx.doi.org/10.1128/aac.00591-22

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