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Gut bacterial extracellular vesicles: important players in regulating intestinal microenvironment
Intestinal microenvironment dysbiosis is one of the major causes of diseases, such as obesity, diabetes, inflammatory bowel disease, and colon cancer. Microbiota-based strategies have excellent clinical potential in the treatment of repetitive and refractory diseases; however, the underlying regulat...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578468/ https://www.ncbi.nlm.nih.gov/pubmed/36242585 http://dx.doi.org/10.1080/19490976.2022.2134689 |
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author | Liang, Xiao Dai, Nini Sheng, Kangliang Lu, Hengqian Wang, Jingmin Chen, Liping Wang, Yongzhong |
author_facet | Liang, Xiao Dai, Nini Sheng, Kangliang Lu, Hengqian Wang, Jingmin Chen, Liping Wang, Yongzhong |
author_sort | Liang, Xiao |
collection | PubMed |
description | Intestinal microenvironment dysbiosis is one of the major causes of diseases, such as obesity, diabetes, inflammatory bowel disease, and colon cancer. Microbiota-based strategies have excellent clinical potential in the treatment of repetitive and refractory diseases; however, the underlying regulatory mechanisms remain elusive. Identification of the internal regulatory mechanism of the gut microbiome and the interaction mechanisms involving bacteria-host is essential to achieve precise control of the gut microbiome and obtain effective clinical data. Gut bacteria-derived extracellular vesicles (GBEVs) are lipid bilayer nanoparticles secreted by the gut microbiota and are considered key players in bacteria-bacteria and bacteria-host communication. This review focusses on the role of GBEVs in gut microbiota interactions and bacteria-host communication, and the potential clinical applications of GBEVs. |
format | Online Article Text |
id | pubmed-9578468 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-95784682022-10-19 Gut bacterial extracellular vesicles: important players in regulating intestinal microenvironment Liang, Xiao Dai, Nini Sheng, Kangliang Lu, Hengqian Wang, Jingmin Chen, Liping Wang, Yongzhong Gut Microbes Review Intestinal microenvironment dysbiosis is one of the major causes of diseases, such as obesity, diabetes, inflammatory bowel disease, and colon cancer. Microbiota-based strategies have excellent clinical potential in the treatment of repetitive and refractory diseases; however, the underlying regulatory mechanisms remain elusive. Identification of the internal regulatory mechanism of the gut microbiome and the interaction mechanisms involving bacteria-host is essential to achieve precise control of the gut microbiome and obtain effective clinical data. Gut bacteria-derived extracellular vesicles (GBEVs) are lipid bilayer nanoparticles secreted by the gut microbiota and are considered key players in bacteria-bacteria and bacteria-host communication. This review focusses on the role of GBEVs in gut microbiota interactions and bacteria-host communication, and the potential clinical applications of GBEVs. Taylor & Francis 2022-10-15 /pmc/articles/PMC9578468/ /pubmed/36242585 http://dx.doi.org/10.1080/19490976.2022.2134689 Text en © 2022 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Liang, Xiao Dai, Nini Sheng, Kangliang Lu, Hengqian Wang, Jingmin Chen, Liping Wang, Yongzhong Gut bacterial extracellular vesicles: important players in regulating intestinal microenvironment |
title | Gut bacterial extracellular vesicles: important players in regulating intestinal microenvironment |
title_full | Gut bacterial extracellular vesicles: important players in regulating intestinal microenvironment |
title_fullStr | Gut bacterial extracellular vesicles: important players in regulating intestinal microenvironment |
title_full_unstemmed | Gut bacterial extracellular vesicles: important players in regulating intestinal microenvironment |
title_short | Gut bacterial extracellular vesicles: important players in regulating intestinal microenvironment |
title_sort | gut bacterial extracellular vesicles: important players in regulating intestinal microenvironment |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578468/ https://www.ncbi.nlm.nih.gov/pubmed/36242585 http://dx.doi.org/10.1080/19490976.2022.2134689 |
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