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Widespread expression of the ancient HERV-K (HML-2) provirus group in normal human tissues

Human endogenous retrovirus (HERV) transcripts are known to be highly expressed in cancers, yet their activity in nondiseased tissue is largely unknown. Using the GTEx RNA-seq dataset from normal tissue sampled at autopsy, we characterized individual expression of the recent HERV-K (HML-2) provirus...

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Detalles Bibliográficos
Autores principales: Burn, Aidan, Roy, Farrah, Freeman, Michael, Coffin, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578601/
https://www.ncbi.nlm.nih.gov/pubmed/36256614
http://dx.doi.org/10.1371/journal.pbio.3001826