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DSCN: Double-target selection guided by CRISPR screening and network

Cancer is a complex disease with usually multiple disease mechanisms. Target combination is a better strategy than a single target in developing cancer therapies. However, target combinations are generally more difficult to be predicted. Current CRISPR-cas9 technology enables genome-wide screening f...

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Detalles Bibliográficos
Autores principales: Liu, Enze, Wu, Xue, Wang, Lei, Huo, Yang, Wu, Huanmei, Li, Lang, Cheng, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578612/
https://www.ncbi.nlm.nih.gov/pubmed/35984840
http://dx.doi.org/10.1371/journal.pcbi.1009421

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