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DSCN: Double-target selection guided by CRISPR screening and network
Cancer is a complex disease with usually multiple disease mechanisms. Target combination is a better strategy than a single target in developing cancer therapies. However, target combinations are generally more difficult to be predicted. Current CRISPR-cas9 technology enables genome-wide screening f...
Autores principales: | Liu, Enze, Wu, Xue, Wang, Lei, Huo, Yang, Wu, Huanmei, Li, Lang, Cheng, Lijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578612/ https://www.ncbi.nlm.nih.gov/pubmed/35984840 http://dx.doi.org/10.1371/journal.pcbi.1009421 |
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