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Analytical and clinical validation of a custom 15-gene next-generation sequencing panel for the evaluation of circulating tumor DNA mutations in patients with advanced non-small-cell lung cancer

BACKGROUND: This is a pilot proof-of-concept study to evaluate the utility of a custom 15-gene circulating tumor DNA (ctDNA) panel as a potential companion molecular next-generation sequencing (NGS) assay for identifying somatic single nucleotide variants and indels in non-small-cell lung cancer (NS...

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Detalles Bibliográficos
Autores principales:	Chow, Yock Ping, Zainul Abidin, Norziha, Kow, Ken Siong, Tho, Lye Mun, Wong, Chieh Lee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578623/ https://www.ncbi.nlm.nih.gov/pubmed/36256645 http://dx.doi.org/10.1371/journal.pone.0276161

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