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Structural, Dynamical, and Entropic Differences between SARS-CoV and SARS-CoV-2 s2m Elements Using Molecular Dynamics Simulations

[Image: see text] The functional role of the highly conserved stem-loop II motif (s2m) in SARS-CoV and SARS-CoV-2 in the viral lifecycle remains enigmatic and an intense area of research. Structure and dynamics of the s2m are key to establishing a structure–function connection, yet a full set of ato...

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Detalles Bibliográficos
Autores principales:	Kensinger, Adam H., Makowski, Joseph A., Pellegrene, Kendy A., Imperatore, Joshua A., Cunningham, Caylee L., Frye, Caleb J., Lackey, Patrick E., Mihailescu, Mihaela Rita, Evanseck, Jeffrey D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578647/ https://www.ncbi.nlm.nih.gov/pubmed/36711027 http://dx.doi.org/10.1021/acsphyschemau.2c00032

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