Integrated computational approach towards identification of HSPG and ACE2 mimicking moieties for SARS-CoV-2 inhibition

A key step to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is to prevent the entry of the virus into the host cells. The receptor-binding domains (RBDs) of spike proteins of SARS-CoV and other human coronaviruses utilize heparan sulfate proteoglycans (HSPGs) as the...

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Detalles Bibliográficos
Autores principales: Sreekumar, Sreya, M. Kuthe, Abhaykumar, Chandra Tripathi, Satyendra, C. Patil, Ganesh, Ravikumar, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578758/
https://www.ncbi.nlm.nih.gov/pubmed/36276265
http://dx.doi.org/10.1016/j.molliq.2022.120566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578758/
https://www.ncbi.nlm.nih.gov/pubmed/36276265
http://dx.doi.org/10.1016/j.molliq.2022.120566

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