Validierungsstudie des MEP-Fragebogens zur erleichterten Erkennung von COPD-Exazerbationen

The Questionnaire “Monitoring of Exacerbation Probability” (MEP) provides a novel simple tool to assist detection and semiquantitative numerical documentation of exacerbation (ECOPD) in daily routine. In a prospective multi-center trial involving 3751 visits of 810 patients in 21 centers, MEP was ev...

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Autores principales: Hering, Thomas, Krinner, Axel, Bulenda, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578762/
https://www.ncbi.nlm.nih.gov/pubmed/36257306
http://dx.doi.org/10.1055/a-1925-7281
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author Hering, Thomas
Krinner, Axel
Bulenda, Dietmar
author_facet Hering, Thomas
Krinner, Axel
Bulenda, Dietmar
author_sort Hering, Thomas
collection PubMed
description The Questionnaire “Monitoring of Exacerbation Probability” (MEP) provides a novel simple tool to assist detection and semiquantitative numerical documentation of exacerbation (ECOPD) in daily routine. In a prospective multi-center trial involving 3751 visits of 810 patients in 21 centers, MEP was evaluated and compared to the application of the EXACT-Pro questionnaire under real world conditions. The population of COPD patients included in this study is a typical COPD population demographically and clinically. Defining a MEP score of one or more as a positive test result, we found a sensitivity of 91% and a specificity of 66%. Additionally, MEP results correlated clearly with EXACT-Pro results. This qualifies the MEP questionnaire as a valid tool for the detection of ECOPD and longitudinal characterization of COPD patients.
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spelling pubmed-95787622022-10-19 Validierungsstudie des MEP-Fragebogens zur erleichterten Erkennung von COPD-Exazerbationen Hering, Thomas Krinner, Axel Bulenda, Dietmar Pneumologie The Questionnaire “Monitoring of Exacerbation Probability” (MEP) provides a novel simple tool to assist detection and semiquantitative numerical documentation of exacerbation (ECOPD) in daily routine. In a prospective multi-center trial involving 3751 visits of 810 patients in 21 centers, MEP was evaluated and compared to the application of the EXACT-Pro questionnaire under real world conditions. The population of COPD patients included in this study is a typical COPD population demographically and clinically. Defining a MEP score of one or more as a positive test result, we found a sensitivity of 91% and a specificity of 66%. Additionally, MEP results correlated clearly with EXACT-Pro results. This qualifies the MEP questionnaire as a valid tool for the detection of ECOPD and longitudinal characterization of COPD patients. Georg Thieme Verlag KG 2022-10-18 /pmc/articles/PMC9578762/ /pubmed/36257306 http://dx.doi.org/10.1055/a-1925-7281 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/). https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Hering, Thomas
Krinner, Axel
Bulenda, Dietmar
Validierungsstudie des MEP-Fragebogens zur erleichterten Erkennung von COPD-Exazerbationen
title Validierungsstudie des MEP-Fragebogens zur erleichterten Erkennung von COPD-Exazerbationen
title_full Validierungsstudie des MEP-Fragebogens zur erleichterten Erkennung von COPD-Exazerbationen
title_fullStr Validierungsstudie des MEP-Fragebogens zur erleichterten Erkennung von COPD-Exazerbationen
title_full_unstemmed Validierungsstudie des MEP-Fragebogens zur erleichterten Erkennung von COPD-Exazerbationen
title_short Validierungsstudie des MEP-Fragebogens zur erleichterten Erkennung von COPD-Exazerbationen
title_sort validierungsstudie des mep-fragebogens zur erleichterten erkennung von copd-exazerbationen
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578762/
https://www.ncbi.nlm.nih.gov/pubmed/36257306
http://dx.doi.org/10.1055/a-1925-7281
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