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Cooperative assembly of filopodia by the formin FMNL2 and I-BAR domain protein IRTKS

Filopodia are long finger-like actin-based structures that project out from the plasma membrane as cells navigate and explore their extracellular environment. The initiation of filopodia formation requires release of tension at the plasma membrane followed by the coordinated assembly of long unbranc...

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Detalles Bibliográficos
Autores principales: Fox, Sarah, Tran, Amanda, Trinkle-Mulcahy, Laura, Copeland, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579038/
https://www.ncbi.nlm.nih.gov/pubmed/36259517
http://dx.doi.org/10.1016/j.jbc.2022.102512