Ionizing Radiation Drives Key Regulators of Antigen Presentation and a Global Expansion of the Immunopeptidome

Little is known about the pathways regulating MHC antigen presentation and the identity of treatment-specific T cell antigens induced by ionizing radiation. For this reason, we investigated the radiation-specific changes in the colorectal tumor cell proteome. We found an increase in DDX58 and ZBP1 p...

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Detalles Bibliográficos
Autores principales: Tailor, Arun, Estephan, Hala, Parker, Robert, Woodhouse, Isaac, Abdulghani, Majd, Nicastri, Annalisa, Jones, Keaton, Salatino, Silvia, Muschel, Ruth, Humphrey, Timothy, Giaccia, Amato, Ternette, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579046/
https://www.ncbi.nlm.nih.gov/pubmed/36089194
http://dx.doi.org/10.1016/j.mcpro.2022.100410

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