Relaxin/insulin-like family peptide receptor 4 (Rxfp4) expressing hypothalamic neurons modulate food intake and preference in mice

OBJECTIVE: Insulin-like peptide 5 (INSL5) signalling, through its cognate receptor relaxin/insulin-like family peptide receptor 4 (RXFP4), has been reported to be orexigenic, and the high fat diet (HFD) preference observed in wildtype mice is altered in Rxfp4 knock-out mice. In this study, we used a...

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Detalles Bibliográficos
Autores principales: Lewis, Jo E., Woodward, Orla RM., Nuzzaci, Danaé, Smith, Christopher A., Adriaenssens, Alice E., Billing, Lawrence, Brighton, Cheryl, Phillips, Benjamin U., Tadross, John A., Kinston, Sarah J., Ciabatti, Ernesto, Göttgens, Berthold, Tripodi, Marco, Hornigold, David, Baker, David, Gribble, Fiona M., Reimann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579047/
https://www.ncbi.nlm.nih.gov/pubmed/36184065
http://dx.doi.org/10.1016/j.molmet.2022.101604

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