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Feeding tube use is associated with severe scoliosis in patients with cerebral palsy and limited ambulatory ability

PURPOSE: Cerebral palsy (CP) is the most common motor disorder in childhood. Scoliosis is a common complication of CP that can reach clinically severe levels, but predictors for scoliosis in CP are not well understood. Some variables identified in the literature involve the severity of the brain inj...

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Autores principales: Yoo, Nicholas, Arand, Brian, Shi, Junxin, Yang, Jingzhen, Noritz, Garey, Whitaker, Amanda T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579063/
https://www.ncbi.nlm.nih.gov/pubmed/35764871
http://dx.doi.org/10.1007/s43390-022-00540-6
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author Yoo, Nicholas
Arand, Brian
Shi, Junxin
Yang, Jingzhen
Noritz, Garey
Whitaker, Amanda T.
author_facet Yoo, Nicholas
Arand, Brian
Shi, Junxin
Yang, Jingzhen
Noritz, Garey
Whitaker, Amanda T.
author_sort Yoo, Nicholas
collection PubMed
description PURPOSE: Cerebral palsy (CP) is the most common motor disorder in childhood. Scoliosis is a common complication of CP that can reach clinically severe levels, but predictors for scoliosis in CP are not well understood. Some variables identified in the literature involve the severity of the brain injury and the presence of hip deformity. We aimed to identify associations with developing severe scoliosis in a prospective cohort of patients with cerebral palsy at higher risk for severe curve progression. METHODS: This study reviewed a prospectively collected database at a tertiary children’s hospital. We evaluated a panel of potential associations with severe scoliosis—including age, sex, Gross Motor Function Classification System (GMFCS) class, history of hip surgery, epilepsy, and feeding tube presence—in a population of children with limited ambulatory ability defined as GMFCS level IV or V CP. Univariate analysis and multivariate logistic regression with stepwise selection was used for analysis. RESULTS: Descriptive analysis showed that female sex, higher GMFCS class, history of hip surgery, non-upright seating, pelvic obliquity, presence of epilepsy, and presence of a feeding tube were associated with an increased risk for scoliosis. Multivariate logistic regression analysis revealed that the presence of a feeding tube was associated with severe scoliosis even when controlling for GMFCS and age. CONCLUSIONS: Feeding tube use may stratify risk for severe scoliosis progression in patients with GMFCS IV or V CP.
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spelling pubmed-95790632022-10-20 Feeding tube use is associated with severe scoliosis in patients with cerebral palsy and limited ambulatory ability Yoo, Nicholas Arand, Brian Shi, Junxin Yang, Jingzhen Noritz, Garey Whitaker, Amanda T. Spine Deform Case Series PURPOSE: Cerebral palsy (CP) is the most common motor disorder in childhood. Scoliosis is a common complication of CP that can reach clinically severe levels, but predictors for scoliosis in CP are not well understood. Some variables identified in the literature involve the severity of the brain injury and the presence of hip deformity. We aimed to identify associations with developing severe scoliosis in a prospective cohort of patients with cerebral palsy at higher risk for severe curve progression. METHODS: This study reviewed a prospectively collected database at a tertiary children’s hospital. We evaluated a panel of potential associations with severe scoliosis—including age, sex, Gross Motor Function Classification System (GMFCS) class, history of hip surgery, epilepsy, and feeding tube presence—in a population of children with limited ambulatory ability defined as GMFCS level IV or V CP. Univariate analysis and multivariate logistic regression with stepwise selection was used for analysis. RESULTS: Descriptive analysis showed that female sex, higher GMFCS class, history of hip surgery, non-upright seating, pelvic obliquity, presence of epilepsy, and presence of a feeding tube were associated with an increased risk for scoliosis. Multivariate logistic regression analysis revealed that the presence of a feeding tube was associated with severe scoliosis even when controlling for GMFCS and age. CONCLUSIONS: Feeding tube use may stratify risk for severe scoliosis progression in patients with GMFCS IV or V CP. Springer International Publishing 2022-06-28 2022 /pmc/articles/PMC9579063/ /pubmed/35764871 http://dx.doi.org/10.1007/s43390-022-00540-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Case Series
Yoo, Nicholas
Arand, Brian
Shi, Junxin
Yang, Jingzhen
Noritz, Garey
Whitaker, Amanda T.
Feeding tube use is associated with severe scoliosis in patients with cerebral palsy and limited ambulatory ability
title Feeding tube use is associated with severe scoliosis in patients with cerebral palsy and limited ambulatory ability
title_full Feeding tube use is associated with severe scoliosis in patients with cerebral palsy and limited ambulatory ability
title_fullStr Feeding tube use is associated with severe scoliosis in patients with cerebral palsy and limited ambulatory ability
title_full_unstemmed Feeding tube use is associated with severe scoliosis in patients with cerebral palsy and limited ambulatory ability
title_short Feeding tube use is associated with severe scoliosis in patients with cerebral palsy and limited ambulatory ability
title_sort feeding tube use is associated with severe scoliosis in patients with cerebral palsy and limited ambulatory ability
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579063/
https://www.ncbi.nlm.nih.gov/pubmed/35764871
http://dx.doi.org/10.1007/s43390-022-00540-6
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