Protein synthesis inhibition and loss of homeostatic functions in astrocytes from an Alzheimer’s disease mouse model: a role for ER-mitochondria interaction

Deregulation of protein synthesis and ER stress/unfolded protein response (ER stress/UPR) have been reported in astrocytes. However, the relationships between protein synthesis deregulation and ER stress/UPR, as well as their role in the altered homeostatic support of Alzheimer’s disease (AD) astroc...

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Detalles Bibliográficos
Autores principales: Tapella, Laura, Dematteis, Giulia, Moro, Marianna, Pistolato, Beatrice, Tonelli, Elisa, Vanella, Virginia Vita, Giustina, Daniele, La Forgia, Aleida, Restelli, Elena, Barberis, Elettra, Cali, Tito, Brini, Marisa, Villani, Salvatore, Del Grosso, Erika, Grilli, Mariagrazia, Manfredi, Marcello, Corazzari, Marco, Grolla, Ambra A., Genazzani, Armando A., Lim, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579125/
https://www.ncbi.nlm.nih.gov/pubmed/36257957
http://dx.doi.org/10.1038/s41419-022-05324-4

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