The role of E3 ubiquitin ligase WWP2 and the regulation of PARP1 by ubiquitinated degradation in acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) has been a huge threat for people's health and finding effective target therapy is urgent and important. WWP2, as one of E3 ubiquitin ligase, is involved in many biological processes by specifically binding to substrates. PARP1 plays a role in cell apoptosis a...

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Detalles Bibliográficos
Autores principales: Lu, Xinxin, Huang, Xinyue, Xu, Haiqi, Lu, Saien, You, Shilong, Xu, Jiaqi, Zhan, Qianru, Dong, Chao, Zhang, Ning, Zhang, Ying, Cao, Liu, Zhang, Xingang, Zhang, Naijin, Zhang, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579143/
https://www.ncbi.nlm.nih.gov/pubmed/36257929
http://dx.doi.org/10.1038/s41420-022-01209-9

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