Rational design of the zonulin inhibitor AT1001 derivatives as potential anti SARS-CoV-2

Although vaccines are greatly mitigating the worldwide pandemic diffusion of SARS-Cov-2, therapeutics should provide many distinct advantages as complementary approach to control the viral spreading. Here, we report the development of new tripeptide derivatives of AT1001 against SARS-CoV-2 M(pro). B...

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Detalles Bibliográficos
Autores principales: Di Micco, Simone, Rahimova, Rahila, Sala, Marina, Scala, Maria C., Vivenzio, Giovanni, Musella, Simona, Andrei, Graciela, Remans, Kim, Mammri, Léa, Snoeck, Robert, Bifulco, Giuseppe, Di Matteo, Francesca, Vestuto, Vincenzo, Campiglia, Pietro, Márquez, José A., Fasano, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579148/
https://www.ncbi.nlm.nih.gov/pubmed/36332548
http://dx.doi.org/10.1016/j.ejmech.2022.114857

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