Deficiency of the Two-Pore Potassium Channel KCNK9 Impairs Intestinal Epithelial Cell Survival and Aggravates Dextran Sodium Sulfate-Induced Colitis

BACKGROUND & AIMS: The 2-pore potassium channel subfamily K member 9 (KCNK9) regulates intracellular calcium concentration and thus modulates cell survival and inflammatory signaling pathways. It also was recognized as a risk allele for inflammatory bowel disease. However, it remains unclear whe...

Descripción completa

Detalles Bibliográficos
Autores principales: Pfeuffer, Steffen, Müntefering, Thomas, Rolfes, Leoni, Straeten, Frederike Anne, Eichler, Susann, Gruchot, Joel, Dobelmann, Vera, Prozorovski, Tim, Görg, Boris, Vucur, Mihael, Berndt, Carsten, Küry, Patrick, Ruck, Tobias, Bittner, Stefan, Bettenworth, Dominik, Budde, Thomas, Lüdde, Tom, Meuth, Sven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579309/
https://www.ncbi.nlm.nih.gov/pubmed/35973573
http://dx.doi.org/10.1016/j.jcmgh.2022.08.003

Ejemplares similares

Ejemplares similares