Predictive performance and verification of physiologically based pharmacokinetic model of propylthiouracil

Background: Propylthiouracil (PTU) treats hyperthyroidism and thyroid crisis in all age groups. A variety of serious adverse effects can occur during clinical use and require attention to its pharmacokinetic and pharmacodynamic characteristics in various populations. Objective: To provide informatio...

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Detalles Bibliográficos
Autores principales: Shen, Chaozhuang, Liang, Dahu, Wang, Xiaohu, Shao, Wenxin, Geng, Kuo, Wang, Xingwen, Sun, Hua, Xie, Haitang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579312/
https://www.ncbi.nlm.nih.gov/pubmed/36278167
http://dx.doi.org/10.3389/fphar.2022.1013432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579312/
https://www.ncbi.nlm.nih.gov/pubmed/36278167
http://dx.doi.org/10.3389/fphar.2022.1013432

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