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Predictive performance and verification of physiologically based pharmacokinetic model of propylthiouracil

Background: Propylthiouracil (PTU) treats hyperthyroidism and thyroid crisis in all age groups. A variety of serious adverse effects can occur during clinical use and require attention to its pharmacokinetic and pharmacodynamic characteristics in various populations. Objective: To provide informatio...

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Detalles Bibliográficos
Autores principales:	Shen, Chaozhuang, Liang, Dahu, Wang, Xiaohu, Shao, Wenxin, Geng, Kuo, Wang, Xingwen, Sun, Hua, Xie, Haitang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579312/ https://www.ncbi.nlm.nih.gov/pubmed/36278167 http://dx.doi.org/10.3389/fphar.2022.1013432

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