Cargando…
Spectral flow cytometry cluster analysis of therapeutic donor lymphocyte infusions identifies T cell subsets associated with outcome in patients with AML relapse
Identification of immune phenotypes linked to durable graft-versus-leukemia (GVL) response following donor lymphocyte infusions (DLI) is of high clinical relevance. In this prospective observational study of 13 AML relapse patients receiving therapeutic DLI, we longitudinally investigated changes in...
Autores principales: | Odak, Ivan, Sikora, Ruth, Riemann, Lennart, Bayir, Lâle M., Beck, Maleen, Drenker, Melanie, Xiao, Yankai, Schneider, Jessica, Dammann, Elke, Stadler, Michael, Eder, Matthias, Ganser, Arnold, Förster, Reinhold, Koenecke, Christian, Schultze-Florey, Christian R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579313/ https://www.ncbi.nlm.nih.gov/pubmed/36275657 http://dx.doi.org/10.3389/fimmu.2022.999163 |
Ejemplares similares
-
Distribution of major lymphocyte subsets and memory T-cell subpopulations in healthy adults employing GLP-conforming multicolor flow cytometry
por: Schultze-Florey, Christian R., et al.
Publicado: (2021) -
Clonal expansion of CD8(+) T cells reflects graft-versus-leukemia activity and precedes durable remission following DLI
por: Schultze-Florey, Christian R., et al.
Publicado: (2021) -
Healthy-like CD4(+) Regulatory and CD4(+) Conventional T-Cell Receptor Repertoires Predict Protection from GVHD Following Donor Lymphocyte Infusion
por: Schneider, Jessica, et al.
Publicado: (2022) -
Donor-derived IL-17A and IL-17F deficiency triggers Th1 allo-responses and increases gut leakage during acute GVHD
por: Odak, Ivan, et al.
Publicado: (2020) -
MRD as Biomarker for Response to Donor Lymphocyte Infusion after Allogeneic Hematopoietic Cell Transplantation in Patients with AML
por: Teich, Katrin, et al.
Publicado: (2023)