Implementing a pragmatic clinical trial to tailor opioids for acute pain on behalf of the IGNITE ADOPT PGx investigators

Opioid prescribing for postoperative pain management is challenging because of inter‐patient variability in opioid response and concern about opioid addiction. Tramadol, hydrocodone, and codeine depend on the cytochrome P450 2D6 (CYP2D6) enzyme for formation of highly potent metabolites. Individuals...

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Detalles Bibliográficos
Autores principales: Cavallari, Larisa H., Cicali, Emily, Wiisanen, Kristin, Fillingim, Roger B., Chakraborty, Hrishikesh, Myers, Rachel A., Blake, Kathryn V., Asiyanbola, Bolanle, Baye, Jordan F., Bronson, Wesley H., Cook, Kelsey J., Elwood, Erica N., Gray, Chancellor F., Gong, Yan, Hines, Lindsay, Kannry, Joseph, Kucher, Natalie, Lynch, Sheryl, Nguyen, Khoa A., Obeng, Aniwaa Owusu, Pratt, Victoria M., Prieto, Hernan A., Ramos, Michelle, Sadeghpour, Azita, Singh, Rajbir, Rosenman, Marc, Starostik, Petr, Thomas, Cameron D., Tillman, Emma, Dexter, Paul R., Horowitz, Carol R., Orlando, Lori A., Peterson, Josh F., Skaar, Todd C., Van Driest, Sara L., Volpi, Simona, Voora, Deepak, Parvataneni, Hari K., Johnson, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579394/
https://www.ncbi.nlm.nih.gov/pubmed/35899435
http://dx.doi.org/10.1111/cts.13376

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