A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age‐dependent differences in absorption

Little is known about the impact of age on the processes governing human intestinal drug absorption. The Ussing chamber is a system to study drug transport across tissue barriers, but it has not been used to study drug absorption processes in children. This study aimed to explore the feasibility of...

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Detalles Bibliográficos
Autores principales: Streekstra, Eva J., Kiss, Márton, van den Heuvel, Jeroen, Nicolaï, Johan, van den Broek, Petra, Botden, Sanne M. B. I., Stommel, Martijn W. J., van Rijssel, Lara, Ungell, Anna‐Lena, van de Steeg, Evita, Russel, Frans G. M., de Wildt, Saskia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579398/
https://www.ncbi.nlm.nih.gov/pubmed/35962572
http://dx.doi.org/10.1111/cts.13368

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