Opioids and Acute Kidney Injury

Summary: Opioid use and misuse in the United States has been at epidemic proportions and is predicted to increase further in the setting of the Coronavirus disease 19 pandemic. Acute kidney injury is a condition associated with significant morbidity and increased mortality. We review the literature...

Descripción completa

Detalles Bibliográficos
Autores principales: Mallappallil, Mary, Bajracharya, Siddhartha, Salifu, Moro, Yap, Ernie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579435/
https://www.ncbi.nlm.nih.gov/pubmed/33896468
http://dx.doi.org/10.1016/j.semnephrol.2021.02.002
_version_ 1784812181537161216
author Mallappallil, Mary
Bajracharya, Siddhartha
Salifu, Moro
Yap, Ernie
author_facet Mallappallil, Mary
Bajracharya, Siddhartha
Salifu, Moro
Yap, Ernie
author_sort Mallappallil, Mary
collection PubMed
description Summary: Opioid use and misuse in the United States has been at epidemic proportions and is predicted to increase further in the setting of the Coronavirus disease 19 pandemic. Acute kidney injury is a condition associated with significant morbidity and increased mortality. We review the literature on the effect of opioids on kidney function and critically examine the association between opioid use and acute kidney injury and identify at-risk populations in whom opioids should be used with caution. We also discuss the role of biomarkers in elucidating this condition and propose preventive measures, novel therapeutic options, and research directions.
format Online
Article
Text
id pubmed-9579435
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier Inc.
record_format MEDLINE/PubMed
spelling pubmed-95794352022-10-19 Opioids and Acute Kidney Injury Mallappallil, Mary Bajracharya, Siddhartha Salifu, Moro Yap, Ernie Semin Nephrol Article Summary: Opioid use and misuse in the United States has been at epidemic proportions and is predicted to increase further in the setting of the Coronavirus disease 19 pandemic. Acute kidney injury is a condition associated with significant morbidity and increased mortality. We review the literature on the effect of opioids on kidney function and critically examine the association between opioid use and acute kidney injury and identify at-risk populations in whom opioids should be used with caution. We also discuss the role of biomarkers in elucidating this condition and propose preventive measures, novel therapeutic options, and research directions. Elsevier Inc. 2021-01 2021-04-22 /pmc/articles/PMC9579435/ /pubmed/33896468 http://dx.doi.org/10.1016/j.semnephrol.2021.02.002 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Mallappallil, Mary
Bajracharya, Siddhartha
Salifu, Moro
Yap, Ernie
Opioids and Acute Kidney Injury
title Opioids and Acute Kidney Injury
title_full Opioids and Acute Kidney Injury
title_fullStr Opioids and Acute Kidney Injury
title_full_unstemmed Opioids and Acute Kidney Injury
title_short Opioids and Acute Kidney Injury
title_sort opioids and acute kidney injury
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579435/
https://www.ncbi.nlm.nih.gov/pubmed/33896468
http://dx.doi.org/10.1016/j.semnephrol.2021.02.002
work_keys_str_mv AT mallappallilmary opioidsandacutekidneyinjury
AT bajracharyasiddhartha opioidsandacutekidneyinjury
AT salifumoro opioidsandacutekidneyinjury
AT yapernie opioidsandacutekidneyinjury

Ejemplares similares