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A compendium of co-regulated mitoribosomal proteins in pan-cancer uncovers collateral defective events in tumor malignancy
Mitochondria are major organelles responsible for cellular energy and metabolism, and their dysfunction is tightly linked to cancer. The mitochondrial ribosome (mitoribosome) is a protein complex consisting of 82 mitoribosomal proteins (MRPs) encoded by nuclear genes and is essential for mitochondri...
Autores principales: | Chang, Ching-Wen, Wei, Zhuang, Durell, Stewart R., Ma, Lichun, Forgues, Marshonna, Wang, Xin Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579511/ https://www.ncbi.nlm.nih.gov/pubmed/36274950 http://dx.doi.org/10.1016/j.isci.2022.105244 |
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