Glycoalkaloids of Plants in the Family Solanaceae (Nightshade) as Potential Drugs

Worldwide interest in medicinal plants and related drugs is growing because of the increased spectrum of new synthetic drugs. In this context, secondary plant metabolites are most significant. This review analyzes data on the structures and biosyntheses of metabolites such as glycoalkaloids; methods...

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Autores principales: Ostreikova, T. O., Kalinkina, O. V., Bogomolov, N. G., Chernykh, I. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Medicinal Plants
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579588/
https://www.ncbi.nlm.nih.gov/pubmed/36277854
http://dx.doi.org/10.1007/s11094-022-02731-x
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author Ostreikova, T. O.
Kalinkina, O. V.
Bogomolov, N. G.
Chernykh, I. V.
author_facet Ostreikova, T. O.
Kalinkina, O. V.
Bogomolov, N. G.
Chernykh, I. V.
author_sort Ostreikova, T. O.
collection PubMed
description Worldwide interest in medicinal plants and related drugs is growing because of the increased spectrum of new synthetic drugs. In this context, secondary plant metabolites are most significant. This review analyzes data on the structures and biosyntheses of metabolites such as glycoalkaloids; methods for their extraction from plants of the family Solanaceae, particularly potato S. tuberosum; their qualitative and quantitative analysis; biological activity; and toxicity. This information could be useful in the selection of methods for sample preparation and extraction of glycoalkaloids during the search for new plant sources with prospects of creating effective and safe pharmacological agents.
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spelling pubmed-95795882022-10-19 Glycoalkaloids of Plants in the Family Solanaceae (Nightshade) as Potential Drugs Ostreikova, T. O. Kalinkina, O. V. Bogomolov, N. G. Chernykh, I. V. Pharm Chem J Medicinal Plants Worldwide interest in medicinal plants and related drugs is growing because of the increased spectrum of new synthetic drugs. In this context, secondary plant metabolites are most significant. This review analyzes data on the structures and biosyntheses of metabolites such as glycoalkaloids; methods for their extraction from plants of the family Solanaceae, particularly potato S. tuberosum; their qualitative and quantitative analysis; biological activity; and toxicity. This information could be useful in the selection of methods for sample preparation and extraction of glycoalkaloids during the search for new plant sources with prospects of creating effective and safe pharmacological agents. Springer US 2022-10-18 2022 /pmc/articles/PMC9579588/ /pubmed/36277854 http://dx.doi.org/10.1007/s11094-022-02731-x Text en © Springer Science+Business Media, LLC, part of Springer Nature 2022, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Medicinal Plants
Ostreikova, T. O.
Kalinkina, O. V.
Bogomolov, N. G.
Chernykh, I. V.
Glycoalkaloids of Plants in the Family Solanaceae (Nightshade) as Potential Drugs
title Glycoalkaloids of Plants in the Family Solanaceae (Nightshade) as Potential Drugs
title_full Glycoalkaloids of Plants in the Family Solanaceae (Nightshade) as Potential Drugs
title_fullStr Glycoalkaloids of Plants in the Family Solanaceae (Nightshade) as Potential Drugs
title_full_unstemmed Glycoalkaloids of Plants in the Family Solanaceae (Nightshade) as Potential Drugs
title_short Glycoalkaloids of Plants in the Family Solanaceae (Nightshade) as Potential Drugs
title_sort glycoalkaloids of plants in the family solanaceae (nightshade) as potential drugs
topic Medicinal Plants
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579588/
https://www.ncbi.nlm.nih.gov/pubmed/36277854
http://dx.doi.org/10.1007/s11094-022-02731-x
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AT bogomolovng glycoalkaloidsofplantsinthefamilysolanaceaenightshadeaspotentialdrugs
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