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Direct evidence of CRISPR-Cas9-mediated mitochondrial genome editing

Pathogenic mitochondrial DNA (mtDNA) mutations can cause a variety of human diseases. The recent development of genome-editing technologies to manipulate mtDNA, such as mitochondria-targeted DNA nucleases and base editors, offer a promising way for curing mitochondrial diseases caused by mtDNA mutat...

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Detalles Bibliográficos
Autores principales:	Bi, Rui, Li, Yu, Xu, Min, Zheng, Quanzhen, Zhang, Deng-Feng, Li, Xiao, Ma, Guolan, Xiang, Bolin, Zhu, Xiaojia, Zhao, Hui, Huang, Xingxu, Zheng, Ping, Yao, Yong-Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579715/ https://www.ncbi.nlm.nih.gov/pubmed/36275864 http://dx.doi.org/10.1016/j.xinn.2022.100329

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