Selenoprotein K contributes to CD36 subcellular trafficking in hepatocytes by accelerating nascent COPII vesicle formation and aggravates hepatic steatosis

SelenoproteinK (SelK), an endoplasmic reticulum (ER) - resident protein, possesses the property of mediate oxidation resistance and ER - associated protein degradation (ERAD) in several tissues. Here, we found that increased SelK markedly promotes fatty acid translocase (CD36) subcellular traffickin...

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Detalles Bibliográficos
Autores principales: You, Mengyue, Wu, Fan, Gao, Meilin, Chen, Mengyue, Zeng, Shu, Zhang, Yang, Zhao, Wei, Li, Danyang, Wei, Li, Ruan, Xiong Z., Chen, Yaxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579716/
https://www.ncbi.nlm.nih.gov/pubmed/36252341
http://dx.doi.org/10.1016/j.redox.2022.102500

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