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Glutathione peroxidase 2 overexpression promotes malignant progression and cisplatin resistance of KRAS-mutated lung cancer cells

Kirsten rat sarcoma viral oncogene homolog (KRAS) aberrations frequently occur in patients with lung cancer. Oncogenic KRAS is characterized by excessive reactive oxygen species (ROS) accumulation, thus, ROS detoxification may contribute to KRAS-driven lung tumorigenesis. In the present study, the i...

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Detalles Bibliográficos
Autores principales:	Wang, Mei, Chen, Xu, Fu, Guang, Ge, Mingjian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579749/ https://www.ncbi.nlm.nih.gov/pubmed/36222298 http://dx.doi.org/10.3892/or.2022.8422

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