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Primary Carcinosarcoma of the Skin in an African Albino: Case Report and Review of Literature

Albinism results from a deficiency of the protein responsible for melanin production in melanocytes. Albinos are at an increased risk of dermatoses and malignancies. Primary carcinosarcoma of the skin is an exceedingly rare biphasic tumor composed of malignant epithelial and mesenchymal elements wit...

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Detalles Bibliográficos
Autores principales: Ndukwe, Chinedu Onwuka, Chiemeka, Michael Emeka, Menkiti, Felix Emeka, Ezejiofor, Florence Ifeoma, Ike, Gerald Kenechi, Chukwuanukwu, Titus O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OMJ 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579781/
https://www.ncbi.nlm.nih.gov/pubmed/36299803
http://dx.doi.org/10.5001/omj.2022.07
Descripción
Sumario:Albinism results from a deficiency of the protein responsible for melanin production in melanocytes. Albinos are at an increased risk of dermatoses and malignancies. Primary carcinosarcoma of the skin is an exceedingly rare biphasic tumor composed of malignant epithelial and mesenchymal elements with an unclear histogenesis. To our knowledge, this has not been reported in an African albino. Here, we report the index case of this rare tumor in an albino of African descent.