Interrogation of the Pathogen Box reveals small molecule ligands against the mycobacterial trehalose transporter LpqY-SugABC

Tuberculosis, caused by Mycobacterium tuberculosis, claims ∼1.5 million lives annually. Effective chemotherapy is essential to control TB, however the emergence of drug-resistant strains of TB have seriously threatened global attempts to control and eradicate this deadly pathogen. Trehalose recyclin...

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Detalles Bibliográficos
Autores principales: Radhakrishnan, Anjana, Brown, Chelsea M., Guy, Collette S., Cooper, Charlotte, Pacheco-Gomez, Raul, Stansfeld, Phillip J., Fullam, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579956/
https://www.ncbi.nlm.nih.gov/pubmed/36320433
http://dx.doi.org/10.1039/d2md00104g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579956/
https://www.ncbi.nlm.nih.gov/pubmed/36320433
http://dx.doi.org/10.1039/d2md00104g

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