NUPR1 contributes to radiation resistance by maintaining ROS homeostasis via AhR/CYP signal axis in hepatocellular carcinoma

BACKGROUND: Radiotherapy (RT) is one of the major therapeutic approaches to hepatocellular carcinoma (HCC). Ionizing radiation (IR) inducing the generation of reactive oxygen species (ROS) leads to a promising antitumor effect. However, the dysregulation of the redox system often causes radioresista...

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Detalles Bibliográficos
Autores principales: Zhan, Yizhi, Zhang, Zhanqiao, Liu, Yuechen, Fang, Yuan, Xie, Yuwen, Zheng, Yilin, Li, Guoxin, Liang, Li, Ding, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580158/
https://www.ncbi.nlm.nih.gov/pubmed/36258210
http://dx.doi.org/10.1186/s12916-022-02554-3

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