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An explainable COVID-19 detection system based on human sounds
Acoustic signals generated by the human body have often been used as biomarkers to diagnose and monitor diseases. As the pathogenesis of COVID-19 indicates impairments in the respiratory system, digital acoustic biomarkers of COVID-19 are under investigation. In this paper, we explore an accurate an...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580234/ https://www.ncbi.nlm.nih.gov/pubmed/36275047 http://dx.doi.org/10.1016/j.smhl.2022.100332 |
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author | Li, Huining Chen, Xingyu Qian, Xiaoye Chen, Huan Li, Zhengxiong Bhattacharjee, Soumyadeep Zhang, Hanbin Huang, Ming-Chun Xu, Wenyao |
author_facet | Li, Huining Chen, Xingyu Qian, Xiaoye Chen, Huan Li, Zhengxiong Bhattacharjee, Soumyadeep Zhang, Hanbin Huang, Ming-Chun Xu, Wenyao |
author_sort | Li, Huining |
collection | PubMed |
description | Acoustic signals generated by the human body have often been used as biomarkers to diagnose and monitor diseases. As the pathogenesis of COVID-19 indicates impairments in the respiratory system, digital acoustic biomarkers of COVID-19 are under investigation. In this paper, we explore an accurate and explainable COVID-19 diagnosis approach based on human speech, cough, and breath data using the power of machine learning. We first analyze our design space considerations from the data aspect and model aspect. Then, we perform data augmentation, Mel-spectrogram transformation, and develop a deep residual architecture-based model for prediction. Experimental results show that our system outperforms the baseline, with the ROC-AUC result increased by 5.47%. Finally, we perform an interpretation analysis based on the visualization of the activation map to further validate the model. |
format | Online Article Text |
id | pubmed-9580234 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Published by Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95802342022-10-19 An explainable COVID-19 detection system based on human sounds Li, Huining Chen, Xingyu Qian, Xiaoye Chen, Huan Li, Zhengxiong Bhattacharjee, Soumyadeep Zhang, Hanbin Huang, Ming-Chun Xu, Wenyao Smart Health (Amst) Article Acoustic signals generated by the human body have often been used as biomarkers to diagnose and monitor diseases. As the pathogenesis of COVID-19 indicates impairments in the respiratory system, digital acoustic biomarkers of COVID-19 are under investigation. In this paper, we explore an accurate and explainable COVID-19 diagnosis approach based on human speech, cough, and breath data using the power of machine learning. We first analyze our design space considerations from the data aspect and model aspect. Then, we perform data augmentation, Mel-spectrogram transformation, and develop a deep residual architecture-based model for prediction. Experimental results show that our system outperforms the baseline, with the ROC-AUC result increased by 5.47%. Finally, we perform an interpretation analysis based on the visualization of the activation map to further validate the model. Published by Elsevier Inc. 2022-12 2022-10-19 /pmc/articles/PMC9580234/ /pubmed/36275047 http://dx.doi.org/10.1016/j.smhl.2022.100332 Text en © 2022 Published by Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Li, Huining Chen, Xingyu Qian, Xiaoye Chen, Huan Li, Zhengxiong Bhattacharjee, Soumyadeep Zhang, Hanbin Huang, Ming-Chun Xu, Wenyao An explainable COVID-19 detection system based on human sounds |
title | An explainable COVID-19 detection system based on human sounds |
title_full | An explainable COVID-19 detection system based on human sounds |
title_fullStr | An explainable COVID-19 detection system based on human sounds |
title_full_unstemmed | An explainable COVID-19 detection system based on human sounds |
title_short | An explainable COVID-19 detection system based on human sounds |
title_sort | explainable covid-19 detection system based on human sounds |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580234/ https://www.ncbi.nlm.nih.gov/pubmed/36275047 http://dx.doi.org/10.1016/j.smhl.2022.100332 |
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