Immunization of mice with vaccinia virus Tiantan strain yields antibodies cross-reactive with protective antigens of monkeypox virus

• The first study describing the cross-reactivity of antibodies elicited by a Chinese smallpox vaccine against MPXV. • Mice immunized with vaccinia virus Tiantan strain yield antibodies cross-reactive with MPXV protective antigens. • Cross-reactivities of VTT-elicited antibodies against monkeypox pr...

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Detalles Bibliográficos
Autores principales: Yang, Lei, Chen, Yingshan, Li, Sha, Zhou, Yuan, Zhang, Yongli, Pei, Rongjuan, Chen, Xinwen, Wang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580254/
https://www.ncbi.nlm.nih.gov/pubmed/36272712
http://dx.doi.org/10.1016/j.virs.2022.10.004
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author Yang, Lei
Chen, Yingshan
Li, Sha
Zhou, Yuan
Zhang, Yongli
Pei, Rongjuan
Chen, Xinwen
Wang, Yun
author_facet Yang, Lei
Chen, Yingshan
Li, Sha
Zhou, Yuan
Zhang, Yongli
Pei, Rongjuan
Chen, Xinwen
Wang, Yun
author_sort Yang, Lei
collection PubMed
description • The first study describing the cross-reactivity of antibodies elicited by a Chinese smallpox vaccine against MPXV. • Mice immunized with vaccinia virus Tiantan strain yield antibodies cross-reactive with MPXV protective antigens. • Cross-reactivities of VTT-elicited antibodies against monkeypox protective antigens are ranging from 33% to 94%.
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spelling pubmed-95802542022-10-21 Immunization of mice with vaccinia virus Tiantan strain yields antibodies cross-reactive with protective antigens of monkeypox virus Yang, Lei Chen, Yingshan Li, Sha Zhou, Yuan Zhang, Yongli Pei, Rongjuan Chen, Xinwen Wang, Yun Virol Sin Letter • The first study describing the cross-reactivity of antibodies elicited by a Chinese smallpox vaccine against MPXV. • Mice immunized with vaccinia virus Tiantan strain yield antibodies cross-reactive with MPXV protective antigens. • Cross-reactivities of VTT-elicited antibodies against monkeypox protective antigens are ranging from 33% to 94%. Wuhan Institute of Virology, Chinese Academy of Sciences 2022-10-19 /pmc/articles/PMC9580254/ /pubmed/36272712 http://dx.doi.org/10.1016/j.virs.2022.10.004 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Letter
Yang, Lei
Chen, Yingshan
Li, Sha
Zhou, Yuan
Zhang, Yongli
Pei, Rongjuan
Chen, Xinwen
Wang, Yun
Immunization of mice with vaccinia virus Tiantan strain yields antibodies cross-reactive with protective antigens of monkeypox virus
title Immunization of mice with vaccinia virus Tiantan strain yields antibodies cross-reactive with protective antigens of monkeypox virus
title_full Immunization of mice with vaccinia virus Tiantan strain yields antibodies cross-reactive with protective antigens of monkeypox virus
title_fullStr Immunization of mice with vaccinia virus Tiantan strain yields antibodies cross-reactive with protective antigens of monkeypox virus
title_full_unstemmed Immunization of mice with vaccinia virus Tiantan strain yields antibodies cross-reactive with protective antigens of monkeypox virus
title_short Immunization of mice with vaccinia virus Tiantan strain yields antibodies cross-reactive with protective antigens of monkeypox virus
title_sort immunization of mice with vaccinia virus tiantan strain yields antibodies cross-reactive with protective antigens of monkeypox virus
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580254/
https://www.ncbi.nlm.nih.gov/pubmed/36272712
http://dx.doi.org/10.1016/j.virs.2022.10.004
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