Intrapleural infusion of tumor cell-derived microparticles packaging methotrexate or saline combined with pemetrexed-cisplatin chemotherapy for the treatment of malignant pleural effusion in advanced non-squamous non-small cell lung cancer: A double-blind, randomized, placebo-controlled study

BACKGROUND: Preclincal studies showed the promising efficacy of tumor cell-derived microparticles packaging methotrexate (TMPs-MTX) to treat advanced non-squamous non-small cell lung cancer (NSCLC) with malignant pleural effusion (MPE). METHODS: This randomized, double-blind, placebo-controlled stud...

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Detalles Bibliográficos
Autores principales: Dong, Xiaorong, Huang, Yu, Yi, Tienan, Hu, Chunhong, Gao, Quanli, Chen, Yuan, Zhang, Jing, Chen, Jianhua, Liu, Li, Meng, Rui, Zhang, Sheng, Dai, Xiaofang, Fei, Shihong, Jin, Yang, Yin, Ping, Hu, Yanping, Wu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580337/
https://www.ncbi.nlm.nih.gov/pubmed/36275698
http://dx.doi.org/10.3389/fimmu.2022.1002938

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