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Rapid transmission and tight bottlenecks constrain the evolution of highly transmissible SARS-CoV-2 variants
Transmission bottlenecks limit the spread of novel mutations and reduce the efficiency of natural selection along a transmission chain. Many viruses exhibit tight bottlenecks, and studies of early SARS-CoV-2 lineages identified a bottleneck of 1–3 infectious virions. While increased force of infecti...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cold Spring Harbor Laboratory
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580385/ https://www.ncbi.nlm.nih.gov/pubmed/36263068 http://dx.doi.org/10.1101/2022.10.12.511991 |
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por Bendall, Emily E., Callear, Amy P., Getz, Amy, Goforth, Kendra, Edwards, Drew, Monto, Arnold S., Martin, Emily T., Lauring, Adam S.
Publicado 2023
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Publicado 2023
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