Structural analysis of PpSP15 and PsSP9 sand fly salivary proteins designed with a self-cleavable linker as a live vaccine candidate against cutaneous leishmaniasis

BACKGROUND: Leishmania parasites are deposited in the host through sand fly bites along with sand fly saliva. Therefore, salivary proteins are promising vaccine candidates for controlling leishmaniasis. Herein, two immunogenic salivary proteins, PpSP15 from Phlebotomus papatasi and PsSP9 from Phlebo...

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Detalles Bibliográficos
Autores principales: Lajevardi, Mahya Sadat, Taheri, Tahereh, Gholami, Elham, Seyed, Negar, Rafati, Sima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580450/
https://www.ncbi.nlm.nih.gov/pubmed/36261836
http://dx.doi.org/10.1186/s13071-022-05437-x

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