Development of Cu(ii)-specific peptide shuttles capable of preventing Cu–amyloid beta toxicity and importing bioavailable Cu into cells

Copper (Cu) in its ionic forms is an essential element for mammals and its homeostasis is tightly controlled. Accordingly, Cu-dyshomeostasis can be lethal as is the case in the well-established genetic Wilson's and Menkes diseases. In Alzheimer's disease (AD), Cu-accumulation occurs in amy...

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Detalles Bibliográficos
Autores principales: Okafor, Michael, Gonzalez, Paulina, Ronot, Pascale, El Masoudi, Islah, Boos, Anne, Ory, Stéphane, Chasserot-Golaz, Sylvette, Gasman, Stéphane, Raibaut, Laurent, Hureau, Christelle, Vitale, Nicolas, Faller, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580518/
https://www.ncbi.nlm.nih.gov/pubmed/36320914
http://dx.doi.org/10.1039/d2sc02593k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580518/
https://www.ncbi.nlm.nih.gov/pubmed/36320914
http://dx.doi.org/10.1039/d2sc02593k

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