Cargando…

Considerations for Choosing Soluble Immune Markers to Determine Safety of Novel Vaginal Products

Several soluble cytokines have been associated with microbicide-induced cervicovaginal inflammation, non-optimal vaginal microbiota, and risk of HIV acquisition. Many of these biomarkers are used in preclinical assays to estimate the safety of vaginally applied products. However, there are currently...

Descripción completa

Detalles Bibliográficos
Autores principales:	Happel, Anna-Ursula, Sivro, Aida, Liebenberg, Lenine, Passmore, Jo Ann, Mitchell, Caroline M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Reproductive Health
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580790/ https://www.ncbi.nlm.nih.gov/pubmed/36303630 http://dx.doi.org/10.3389/frph.2022.899277

Ejemplares similares

The Impact of Semen Exposure on the Immune and Microbial Environments of the Female Genital Tract
por: Jewanraj, Janine, et al.
Publicado: (2020)

Bugs, drugs, and HIV: the role of the vaginal microbiome in HIV risk and antiretroviral efficacy for HIV prevention
por: Liebenberg, Lenine J. P., et al.
Publicado: (2017)

Systems Analysis Reveals Contraceptive-Induced Alteration of Cervicovaginal Gene Expression in a Randomized Trial
por: Balle, Christina, et al.
Publicado: (2022)

Postmenopausal Vaginal Microbiome and Microbiota
por: de Oliveira, Nayara Santos, et al.
Publicado: (2022)

Characterization of the Ovine Vaginal Microbiome and Inflammation Patterns as an Improved Testing Model of Human Vaginal Irritation
por: Pyles, Richard B., et al.
Publicado: (2021)

The Impact of Over-The-Counter Lactic Acid Containing Vaginal Gels on the Integrity and Inflammatory State of the Vaginal Epithelium in vitro
por: Tyssen, David, et al.
Publicado: (2022)

“Words are too small”: exploring artmaking as a tool to facilitate dialogues with young South African women about their sexual and reproductive health experiences
por: Hartley, Felicity, et al.
Publicado: (2023)

Semen: A modulator of female genital tract inflammation and a vector for HIV‐1 transmission
por: Jewanraj, Janine, et al.
Publicado: (2021)

The Vaginal Virome—Balancing Female Genital Tract Bacteriome, Mucosal Immunity, and Sexual and Reproductive Health Outcomes?
por: Happel, Anna-Ursula, et al.
Publicado: (2020)

Vaginal Microbiomes Associated With Aerobic Vaginitis and Bacterial Vaginosis
por: Kaambo, Evelyn, et al.
Publicado: (2018)

Altered Innate Immunity and Damaged Epithelial Integrity in Vaginal Microbial Dysbiosis
por: Cheu, Ryan K., et al.
Publicado: (2022)

Menstrual tampons and vaginal pessaries: regulation of intravaginal medical devices by the US FDA
por: Pollard, Colin M.
Publicado: (2023)

Preferred product attributes of a multipurpose vaginal ring: Findings from a phase 1 trial
por: Tolley, Elizabeth E., et al.
Publicado: (2023)

Role of short interpregnancy interval, birth mode, birth practices, and the postpartum vaginal microbiome in preterm birth
por: Odogwu, Nkechi Martina
Publicado: (2023)

Considerations in Adolescent Use of the Etonogestrel Subdermal Implant: A Cohort Study
por: Fei, Y. Frances, et al.
Publicado: (2021)

Endometriosis and the Coronavirus (COVID-19) Pandemic: Clinical Advice and Future Considerations
por: Leonardi, Mathew, et al.
Publicado: (2020)

Beyond the Binary: Sexual and Reproductive Health Considerations for Transgender and Gender Expansive Adolescents
por: Lunde, Claire E., et al.
Publicado: (2021)

Development of Gram Stain Scoring System Based on Pro-Inflammatory Cytokines in the Sheep Model for Testing Toxicity of Vaginal Products
por: Vincent, Kathleen L., et al.
Publicado: (2021)

Which vaginal douching agent is the best choice before oocyte retrieval? A systematic review and network meta-analysis
por: Meng, Ying, et al.
Publicado: (2022)

Role of the human vaginal microbiota in the regulation of inflammation and sexually transmitted infection acquisition: Contribution of the non-human primate model to a better understanding?
por: Adapen, Cindy, et al.
Publicado: (2022)

Development of in vitro methods to model the impact of vaginal lactobacilli on Staphylococcus aureus biofilm formation on menstrual cups as well as validation of recommended cleaning directions
por: Friberg, Maria, et al.
Publicado: (2023)

Higher mucosal antibody concentrations in women with genital tract inflammation
por: Sobia, Parveen, et al.
Publicado: (2021)

Bacterial vaginosis: a review of approaches to treatment and prevention
por: Abbe, Carmen, et al.
Publicado: (2023)

Tenofovir vaginal film as a potential MPT product against HIV-1 and HSV-2 acquisition: formulation development and preclinical assessment in non-human primates
por: Patel, Sravan Kumar, et al.
Publicado: (2023)

Participant experiences with a multipurpose vaginal ring for HIV and pregnancy prevention during a phase 1 clinical trial: learning from users to improve acceptability
por: Shapley-Quinn, Mary Kate, et al.
Publicado: (2023)

In Silico Characterisation of Putative Prophages in Lactobacillaceae Used in Probiotics for Vaginal Health
por: Happel, Anna-Ursula, et al.
Publicado: (2022)

Probiotics for vaginal health in South Africa: what is on retailers’ shelves?
por: Happel, Anna-Ursula, et al.
Publicado: (2017)

Safety surveillance for PrEP in pregnant and breastfeeding women
por: Fairlie, Lee, et al.
Publicado: (2023)

Role of Immunity and Vaginal Microbiome in Clearance and Persistence of Human Papillomavirus Infection
por: Ntuli, Lungelo, et al.
Publicado: (2022)

The safety assessment of tampons: illustration of a comprehensive approach for four different products
por: Hochwalt, Anne E., et al.
Publicado: (2023)

CD57 expression by T cells in the female genital tract of HIV-zx1 infected women
por: Liebenberg, Lenine J., et al.
Publicado: (2010)

Genital inflammation undermines the effectiveness of tenofovir gel in preventing HIV acquisition in women
por: McKinnon, Lyle R., et al.
Publicado: (2018)

Efficacy and Safety of Laser Therapy for the Treatment of Genitourinary Syndrome of Menopause: A Protocol for Systematic Review and Meta-Analysis of Clinical Trials
por: Pessoa, Lisieux de Lourdes Martins Nóbrega, et al.
Publicado: (2021)

Support of adult urinary incontinence products: recommendations to assure safety and regulatory compliance through application of a risk assessment framework
por: Krause, Edburga L., et al.
Publicado: (2023)

Safety reporting of Essure medical device: a qualitative and quantitative assessment on the FDA manufacturer and user facility device experience database in 2018
por: Zou, Chenyu, et al.
Publicado: (2023)

Randomized controlled phase IIa clinical trial of safety, pharmacokinetics and pharmacodynamics of tenofovir and tenofovir plus levonorgestrel releasing intravaginal rings used by women in Kenya
por: Mugo, Nelly R., et al.
Publicado: (2023)

Stability and transport of cervical cytobrushes for isolation of mononuclear cells from the female genital tract
por: Liebenberg, Lenine J., et al.
Publicado: (2011)

Presence and Persistence of Putative Lytic and Temperate Bacteriophages in Vaginal Metagenomes from South African Adolescents
por: Happel, Anna-Ursula, et al.
Publicado: (2021)

Obstetric complications in mothers with ADHD
por: Walsh, Caroline J., et al.
Publicado: (2022)

Endometrial Stem/Progenitor Cells–Their Role in Endometrial Repair and Regeneration
por: Cousins, Fiona L., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_quvgti4suaupqudd6fsepkcjn9