Cargando…

Loss of GABARAPL1 confers ferroptosis resistance to cancer stem‐like cells in hepatocellular carcinoma

Cancer stem‐like cells (CSLC) are considered a major contributor to the development and progression of hepatocellular carcinoma (HCC). Previous studies indicated that CSLC are characterized by resistance to ferroptosis, a type of lipid peroxidation‐dependent cell death. Here, we identified a set of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Du, Xiaojing, Qi, Zhuoran, Xu, Jinzhi, Guo, Mengzhou, Zhang, Xingxing, Yu, Zhijie, Cao, Xin, Xia, Jinglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580891/ https://www.ncbi.nlm.nih.gov/pubmed/36062307 http://dx.doi.org/10.1002/1878-0261.13305

Ejemplares similares

Transcriptome and Lipidomic Analysis Suggests Lipid Metabolism Reprogramming and Upregulating SPHK1 Promotes Stemness in Pancreatic Ductal Adenocarcinoma Stem-like Cells
por: Xu, Jinzhi, et al.
Publicado: (2023)

HELLS modulates the stemness of intrahepatic cholangiocarcinoma through promoting senescence-associated secretory phenotype
por: Du, Xiaojing, et al.
Publicado: (2023)

Serum LAG-3 Predicts Outcome and Treatment Response in Hepatocellular Carcinoma Patients With Transarterial Chemoembolization
por: Guo, Mengzhou, et al.
Publicado: (2021)

A new crystal form of GABARAPL2
por: Scicluna, Kristen, et al.
Publicado: (2021)

Specific Distribution of the Autophagic Protein GABARAPL1/GEC1 in the Developing and Adult Mouse Brain and Identification of Neuronal Populations Expressing GABARAPL1/GEC1
por: Le Grand, Jaclyn Nicole, et al.
Publicado: (2013)

MT4‐MMP in tumor‐associated macrophages is linked to hepatocellular carcinoma aggressiveness and recurrence
por: Qi, Feng, et al.
Publicado: (2020)

The autophagy GABARAPL1 gene is epigenetically regulated in breast cancer models
por: Hervouet, Eric, et al.
Publicado: (2015)

The NMD Pathway Regulates GABARAPL1 mRNA during the EMT
por: Baudu, Timothée, et al.
Publicado: (2021)

GABARAPL1 Inhibits EMT Signaling through SMAD-Tageted Negative Feedback
por: Jacquet, Marine, et al.
Publicado: (2021)

Computational Identification of Immune- and Ferroptosis-Related LncRNA Signature for Prognosis of Hepatocellular Carcinoma
por: Huang, Anmin, et al.
Publicado: (2021)

Autophagic Network Analysis of the Dual Effect of Sevoflurane on Neurons Associated with GABARAPL1 and 2
por: Lu, Guolin, et al.
Publicado: (2020)

GABARAPL1 suppresses metastasis by counteracting PI3K/Akt pathway in prostate cancer
por: Su, Wei, et al.
Publicado: (2016)

Insulin Inhibits Autophagy by Inhibiting the Binding of FoXO1 to the Promoter Region of GABARAPL1
por: Hong, Tao, et al.
Publicado: (2023)

Triggering a switch from basal- to luminal-like breast cancer subtype by the small-molecule diptoindonesin G via induction of GABARAPL1
por: Fan, Minmin, et al.
Publicado: (2020)

The Immune System GTPase GIMAP6 Interacts with the Atg8 Homologue GABARAPL2 and Is Recruited to Autophagosomes
por: Pascall, John C., et al.
Publicado: (2013)

Secretion of pro‐angiogenic extracellular vesicles during hypoxia is dependent on the autophagy‐related protein GABARAPL1
por: Keulers, Tom G., et al.
Publicado: (2021)

Correction: Insulin Inhibits Autophagy by Inhibiting the Binding of FoXO1 to the Promoter Region of GABARAPL1
por: Hong, Tao, et al.
Publicado: (2023)

Sulfarotene, a synthetic retinoid, overcomes stemness and sorafenib resistance of hepatocellular carcinoma via suppressing SOS2-RAS pathway
por: Qi, Feng, et al.
Publicado: (2021)

MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis
por: Xu, Pengfei, et al.
Publicado: (2022)

High expression of gabarapl1 is associated with a better outcome for patients with lymph node-positive breast cancer
por: Berthier, A, et al.
Publicado: (2010)

MicroRNA-195 regulates proliferation, migration, angiogenesis and autophagy of endothelial progenitor cells by targeting GABARAPL1
por: Mo, Jianwen, et al.
Publicado: (2016)

GABARAPL1 acts as a potential marker and promotes tumor proliferation and metastasis in triple negative breast cancer
por: Ran, Li, et al.
Publicado: (2017)

Rapid induction of p62 and GABARAPL1 upon proteasome inhibition promotes survival before autophagy activation
por: Sha, Zhe, et al.
Publicado: (2018)

GABARAPL1 tumor suppressive function is independent of its conjugation to autophagosomes in MCF-7 breast cancer cells
por: Poillet-Perez, Laura, et al.
Publicado: (2017)

Comprehensive Metabolic Profiling and Genome-wide Analysis Reveal Therapeutic Modalities for Hepatocellular Carcinoma
por: Qi, Feng, et al.
Publicado: (2023)

Expression and clinical significance of LAG-3, FGL1, PD-L1 and CD8(+)T cells in hepatocellular carcinoma using multiplex quantitative analysis
por: Guo, Mengzhou, et al.
Publicado: (2020)

Omarigliptin inhibits brain cell ferroptosis after intracerebral hemorrhage
por: Zhang, Yan, et al.
Publicado: (2023)

Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs
por: Birgisdottir, Åsa Birna, et al.
Publicado: (2019)

GABARAPL1 Promotes AR+ Prostate Cancer Growth by Increasing FL-AR/AR-V Transcription Activity and Nuclear Translocation
por: Su, Bing, et al.
Publicado: (2019)

Histone lysine demethylase 3B regulates autophagy via transcriptional regulation of GABARAPL1 in acute myeloid leukemia cells
por: Song, Ying, et al.
Publicado: (2023)

Hepatocellular carcinoma: thyroid hormone promotes tumorigenicity through inducing cancer stem-like cell self-renewal
por: Wang, Tao, et al.
Publicado: (2016)

Long Non-coding RNAs Gabarapl2 and Chrnb2 Positively Regulate Inflammatory Signaling in a Mouse Model of Dry Eye
por: Yang, Yuhan, et al.
Publicado: (2021)

Oxidative-Damaged Mitochondria Activate GABARAPL1-Induced NLRP3 Inflammasomes in an Autophagic-Exosome Manner after Acute Myocardial Ischemia
por: Zhang, Tiechun, et al.
Publicado: (2022)

The ATG8 Family Proteins GABARAP and GABARAPL1 Target Antigen to Dendritic Cells to Prime CD4(+) and CD8(+) T Cells
por: Fonderflick, Leïla, et al.
Publicado: (2022)

The mitophagy receptor NIX induces vIRF-1 oligomerization and interaction with GABARAPL1 for the promotion of HHV-8 reactivation-induced mitophagy
por: Vo, Mai Tram, et al.
Publicado: (2023)

Identify an innovative ferroptosis‐related gene in hepatocellular carcinoma
por: Hu, Gangfeng, et al.
Publicado: (2022)

Retracted: Oxidative-Damaged Mitochondria Activate GABARAPL1-Induced NLRP3 Inflammasomes in an Autophagic-Exosome Manner after Acute Myocardial Ischemia
por: Longevity, Oxidative Medicine and Cellular
Publicado: (2023)

Molecular Targets of Ferroptosis in Hepatocellular Carcinoma
por: Liao, Hao, et al.
Publicado: (2021)

The Critical Role of Ferroptosis in Hepatocellular Carcinoma
por: Pan, Fan, et al.
Publicado: (2022)

Tumor Mutation Burden-Associated LINC00638/miR-4732-3p/ULBP1 Axis Promotes Immune Escape via PD-L1 in Hepatocellular Carcinoma
por: Qi, Feng, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qq9fjk0eeulv4sfu92cr7343bu