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Gefitinib enhances the anti-tumor immune response against EGFR-mutated NSCLC by upregulating B7H5 expression and activating T cells via CD28H

Gefitinib is a sensitive and effective drug to treat non-small-cell lung cancer (NSCLC) carrying the somatic activating mutations of the tyrosine kinase domain of epidermal growth factor receptor (EGFR). In the present study, a new mechanism of action of gefitinib in EGFR-mutated NSCLC cells was dis...

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Detalles Bibliográficos
Autores principales:	Guo, Huihui, Zhang, Xilin, Xie, Shangzhi, Chen, Tianwei, Xie, Dong, Cai, Ying, Cui, Dawei, Wang, Liang, Chen, Wei, Wang, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581114/ https://www.ncbi.nlm.nih.gov/pubmed/36205136 http://dx.doi.org/10.3892/ijo.2022.5436

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