Loss of exosomal micro-RNA-200b-3p from hypoxia cancer-associated fibroblasts reduces sensitivity to 5-flourouracil in colorectal cancer through targeting high-mobility group box 3

Hypoxia-mediated tumor progression is a major problem in colorectal cancer (CRC). MicroRNA (miR)-200b-3p can attenuate tumorigenesis in CRC, while exosomal miRNAs derived from cancer-associated fibroblasts (CAFs) can promote cancer progression. Nevertheless, the function of exosomal miR-200b-3p deri...

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Detalles Bibliográficos
Autores principales: Yuan, Hang, Chen, Bingchen, Chai, Rui, Gong, Wenjing, Wan, Ziang, Zheng, Boan, Hu, Xinye, Guo, Yang, Gao, Shan, Dai, Qiaoqiong, Yu, Peng, Tu, Shiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581251/
https://www.ncbi.nlm.nih.gov/pubmed/36276139
http://dx.doi.org/10.3389/fonc.2022.920131

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