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Dynamic but discordant alterations in zDHHC5 expression and palmitoylation of its substrates in cardiac pathologies

S-palmitoylation is an essential lipid modification catalysed by zDHHC-palmitoyl acyltransferases that regulates the localisation and activity of substrates in every class of protein and tissue investigated to date. In the heart, S-palmitoylation regulates sodium-calcium exchanger (NCX1) inactivatio...

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Detalles Bibliográficos
Autores principales: Main, Alice, Boguslavskyi, Andri, Howie, Jacqueline, Kuo, Chien-Wen, Rankin, Aileen, Burton, Francis L., Smith, Godfrey L., Hajjar, Roger, Baillie, George S., Campbell, Kenneth S., Shattock, Michael J., Fuller, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581287/
https://www.ncbi.nlm.nih.gov/pubmed/36277202
http://dx.doi.org/10.3389/fphys.2022.1023237