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Dynamic but discordant alterations in zDHHC5 expression and palmitoylation of its substrates in cardiac pathologies
S-palmitoylation is an essential lipid modification catalysed by zDHHC-palmitoyl acyltransferases that regulates the localisation and activity of substrates in every class of protein and tissue investigated to date. In the heart, S-palmitoylation regulates sodium-calcium exchanger (NCX1) inactivatio...
Autores principales: | Main, Alice, Boguslavskyi, Andri, Howie, Jacqueline, Kuo, Chien-Wen, Rankin, Aileen, Burton, Francis L., Smith, Godfrey L., Hajjar, Roger, Baillie, George S., Campbell, Kenneth S., Shattock, Michael J., Fuller, William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581287/ https://www.ncbi.nlm.nih.gov/pubmed/36277202 http://dx.doi.org/10.3389/fphys.2022.1023237 |
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