Cargando…

Molecular dynamics study of tropical calcific pancreatitis (TCP) associated calcium-sensing receptor single nucleotide variation

Tropical Calcific Pancreatitis (TCP) is a chronic non-alcoholic pancreatitis characterised by extensive calcification. The disease usually appears at a younger age and is more common in tropical regions. This disease’s progression can lead to pancreatic diabetes, which can subsequently lead to pancr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shrivastava, Ashish, Mathur, Kartavya, Verma, Rohit Kumar, Jayadev Magani, Sri Krishna, Vyas, Deepak Krishna, Singh, Ashutosh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581290/ https://www.ncbi.nlm.nih.gov/pubmed/36275616 http://dx.doi.org/10.3389/fmolb.2022.982831

Ejemplares similares

Structural, functional and molecular dynamics analysis of cathepsin B gene SNPs associated with tropical calcific pancreatitis, a rare disease of tropics
por: Singh, Garima, et al.
Publicado: (2019)

Regorafenib and Ruthenium Complex Combination Inhibit Cancer Cell Growth by Targeting PI3K/AKT/ERK Signalling in Colorectal Cancer Cells
por: Sharma, Deepu, et al.
Publicado: (2022)

The malaria parasite chaperonin containing TCP-1 (CCT) complex: Data integration with other CCT proteomes
por: Wilkinson, Mark D., et al.
Publicado: (2022)

The nucleotide exchange factors of Hsp70 molecular chaperones
por: Bracher, Andreas, et al.
Publicado: (2015)

Therminator DNA Polymerase: Modified Nucleotides and Unnatural Substrates
por: Gardner, Andrew F., et al.
Publicado: (2019)

CUTie2: The Attack of the Cyclic Nucleotide Sensor Clones
por: Klein, Florencia, et al.
Publicado: (2021)

Cellular ATP Levels Determine the Stability of a Nucleotide Kinase
por: Brylski, Oliver, et al.
Publicado: (2021)

Editorial: Antiviral drug discovery against pathogens of pandemic concern: Advancements in target site identification and structure-based drug development
por: Padmanabha Das, Krishna M.
Publicado: (2023)

Deep Mutational Scanning of Viral Glycoproteins and Their Host Receptors
por: Narayanan, Krishna K., et al.
Publicado: (2021)

Substrate Protein Interactions and Methylglyoxal Modifications Reduce the Aggregation Propensity of Human Alpha-A-Crystallin G98R Mutant
por: Santhoshkumar, Puttur, et al.
Publicado: (2022)

Ligand-based pharmacophore modeling and QSAR approach to identify potential dengue protease inhibitors
por: Poola, Anushka A., et al.
Publicado: (2023)

Umbrella Review on Associations Between Single Nucleotide Polymorphisms and Lung Cancer Risk
por: Li, Xiaoying, et al.
Publicado: (2021)

Within and Beyond the Nucleotide Addition Cycle of Viral RNA-dependent RNA Polymerases
por: Gong, Peng
Publicado: (2022)

Green Approach: ‘‘A Forwarding Step for Curing Leishmaniasis—A Neglected Tropical Disease’’
por: Sharma, Lakshika, et al.
Publicado: (2021)

The protein kinase CK1: Inhibition, activation, and possible allosteric modulation
por: Sunkari, Yashoda Krishna, et al.
Publicado: (2022)

DETECTing Merkel Cell Polyomavirus in Merkel Tumors
por: Arora, Reety, et al.
Publicado: (2020)

A Single Nucleotide Polymorphism Within Molybdenum Cofactor Sulfurase Gene Is Associated With Neuropsychiatric Conditions
por: Safa, Amin, et al.
Publicado: (2020)

Small GTPase Ran: Depicting the nucleotide-specific conformational landscape of the functionally important C-terminus
por: Czigleczki, Janka, et al.
Publicado: (2023)

Identification of metabolic fingerprints in severe obstructive sleep apnea using gas chromatography–Mass spectrometry
por: Mohit,, et al.
Publicado: (2022)

Editorial: The Role of Calcium Channels in Human Health and Disease
por: Zhang, Peng, et al.
Publicado: (2022)

Nucleotide-Specific Autoinhibition of Full-Length K-Ras4B Identified by Extensive Conformational Sampling
por: Dudas, Balint, et al.
Publicado: (2020)

A non-synonymous single nucleotide polymorphism in SIRT6 predicts neurological severity in Friedreich ataxia
por: Rodden, Layne N., et al.
Publicado: (2022)

Clinical Utility and the Yield of Single Nucleotide Polymorphism Array in Prenatal Diagnosis of Fetal Central Nervous System Abnormalities
por: Cai, Meiying, et al.
Publicado: (2021)

Editorial: Oxidative Damage of RNA: Structure, Function, and Biological Implications - From Nucleotides to Short and Long RNAs in Chemistry and Biology
por: Aung, Lynn Htet Htet, et al.
Publicado: (2022)

Editorial: The role of calcium channels in human health and disease—Volume II
por: Zhang, Peng, et al.
Publicado: (2023)

Impact of a Single Nucleotide Polymorphism on the 3D Protein Structure and Ubiquitination Activity of E3 Ubiquitin Ligase Arkadia
por: Birkou, Maria, et al.
Publicado: (2022)

Radical-SAM dependent nucleotide dehydratase (SAND), rectification of the names of an ancient iron-sulfur enzyme using NC-IUBMB recommendations
por: Ji, Yuxuan, et al.
Publicado: (2022)

Is MYND Domain-Mediated Assembly of SMYD3 Complexes Involved in Calcium Dependent Signaling?
por: Zhang, Yingxue, et al.
Publicado: (2019)

Annexin A3, a Calcium-Dependent Phospholipid-Binding Protein: Implication in Cancer
por: Yang, Liu, et al.
Publicado: (2021)

Prognostic Potential of Secreted Modular Calcium-Binding Protein 1 in Low-Grade Glioma
por: Wang, Jing, et al.
Publicado: (2021)

Conserved gene signatures shared among MAPT mutations reveal defects in calcium signaling
por: Minaya, Miguel A., et al.
Publicado: (2023)

Mechanistic insights into the role of calcium in the allosteric regulation of the calmodulin-regulated death-associated protein kinase
por: Li, Xiaolong, et al.
Publicado: (2022)

mutTCPdb: a comprehensive database for genomic variants of a tropical country neglected disease—tropical calcific pancreatitis
por: Singh, Garima, et al.
Publicado: (2018)

Modeling Calcium Signaling in S. cerevisiae Highlights the Role and Regulation of the Calmodulin-Calcineurin Pathway in Response to Hypotonic Shock
por: Spolaor, Simone, et al.
Publicado: (2022)

Novel Disease-Associated Missense Single-Nucleotide Polymorphisms Variants Predication by Algorithms Tools and Molecular Dynamics Simulation of Human TCIRG1 Gene Causing Congenital Neutropenia and Osteopetrosis
por: Shinwari, Khyber, et al.
Publicado: (2022)

Multi-omic single cell sequencing: Overview and opportunities for kidney disease therapeutic development
por: Pregizer, Steven, et al.
Publicado: (2023)

Functional Analysis of Rare Genetic Variants in the Negative Regulator of Intracellular Calcium Signaling RCAS/SLC10A7
por: Wannowius, Marie, et al.
Publicado: (2021)

Calcium influx, oxidative stress, and apoptosis induced by TRPV1 in chronic myeloid leukemia cells: Synergistic effects with imatinib
por: Maggi, Federica, et al.
Publicado: (2023)

Evolution of Indian Influenza A (H1N1) Hemagglutinin Strains: A Comparative Analysis of the Pandemic Californian HA Strain
por: Pushan, Shilpa Sri, et al.
Publicado: (2023)

Balanced activities of Hsp70 and the ubiquitin proteasome system underlie cellular protein homeostasis
por: Jawed, Areeb, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_rv254mrn8pe1k7vdi4imjuhb28